Mathematical Model for Combined Radiotherapy and Chemotherapy that Fits with Experimental Data

نویسندگان

چکیده

Abstract One of the most challenges to effective treatment cancer is radiation resistance. Published data from a notably experiment performed examine ability compound therapy overcome resistance utilized. The chemotherapeutic drug used was vinblastine. included control tumors and which were treated with radiation, chemotherapy, or both. In this paper mathematical model developed. fits reported mentioned experiment. Starting suggested for tumor growth, expanded include effect radiotherapy, combined chemotherapy radiotherapy. By fitting experimental data, parameters are obtained in each stage. final acquired can be case no treatment, radiotherapy treatment. Results capture behavior all cases reasonable way.

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ژورنال

عنوان ژورنال: Journal of physics

سال: 2022

ISSN: ['0022-3700', '1747-3721', '0368-3508', '1747-3713']

DOI: https://doi.org/10.1088/1742-6596/2287/1/012013